I would like to make it clear that I am not looking forward to an Earthquake on the West Coast or Trouble in the Middle East, however I believe that the Word of God has never been wrong, one third of the Bible is Prophecy, and every Word has come to pass, and so whatever is written for our future will happen.
As a matter of fact when you have had one or more "Road to Damascus experiences" (Paul) you live for Him every minute of every day, tiring to tell other than to seek Him who die for you. Should you study the Bible and the pass fulfilled Prophecies, that alone should convince you, but many treat it as a fairy tale.
Isaiah 17
"The burden of Damascus. Behold, Damascus is taken away from being a city, and it shall be a ruinous heap." -- v 1
There are records of the city of Damascus ranging back into the time of Abraham, and Damascus is considered the oldest continually inhabited city in the world. Here we are told that it will no longer be a city.
In 732 BC, Israel's king Ahaz paid tribute to the Assyrian king Tiglath-Pileser III, asking him to save Israel from the Syrians who were attacking them (2 Kings 16). This lead Assyria to utterly destroy the Syrian capital, Damascus, leaving it completely in ruins.
Many people consider this the fulfilment of the prophecy, but the prophecy itself was written after Tiglath-Pileser III attacked Damascus, and, as Isaiah mentions the death of Ahaz earlier in Isaiah 14 v 28, it is assumed the prophecy was written after the death of Ahaz. His death occurred in 715 BC, 17 years after the destruction of Damascus, so obviously the prophecy is for a later time.
Currently Damascus, the capital of Syria, provides the main supply of weapons to Israel's enemies. It is interesting that this city has an entire chapter mentioning its utter destruction considering its high animosity towards Israel at the present time.
"The cities of Aroer are forsaken: they shall be for flocks, which shall lie down, and none shall make them afraid. The fortress also shall cease from Ephraim, and the kingdom from Damascus, and the remnant of Syria: they shall be as the glory of the children of Israel, saith the LORD of hosts. And in that day it shall come to pass, that the glory of Jacob shall be made thin, and the fatness of his flesh shall wax lean." -- v 2-3
Aroer, which is in Jordan, will be deserted. And not only will Syria have its power taken away, becoming a heap of ruins, but Israel shall be severely weakened and its strongholds destroyed.
"In that day shall his strong cities be as a forsaken bough, and an uppermost branch, which they left because of the children of Israel: and there shall be desolation. Because thou hast forgotten the God of thy salvation, and hast not been mindful of the rock of thy strength, therefore shalt thou plant pleasant plants, and shalt set it with strange slips:" -- v 9 - 10
Israel's loss will be because it no longer considers God, but the result is that Israel will be drawn back to God:
"At that day shall a man look to his Maker, and his eyes shall have respect to the Holy One of Israel." -- v 7
"Woe to the multitude of many people, which make a noise like the noise of the seas; and to the rushing of nations, that make a rushing like the rushing of mighty waters! The nations shall rush like the rushing of many waters: but God shall rebuke them, and they shall flee far off, and shall be chased as the chaff of the mountains before the wind, and like a rolling thing before the whirlwind. And behold at eveningtide trouble; and before the morning he is not. This is the portion of them that spoil us, and the lot of them that rob us."-- v 12 - 14
The result of the war, even though it leaves Israel severely hurt, will be that Israel's enemies shall be destroyed overnight. Again, the reference to Tiglath Pileser IIIs destruction of Damascus does not reflect the prophecy here, as there was no account of multiple nations attacking Israel together during that time.